Get started

Get started

Sweet Shield: How Honey May Slow Down Glucose Absorption in the Gut

Sweet Shield: How Honey May Slow Down Glucose Absorption in the Gut

Honey contains enzymes that may slow glucose absorption and reduce sugar spikes. This blog explores how diabetics can include honey safely—with portion control and CGM monitoring.

Heald Membership: Your Path to Diabetes Reversal

how honey imapcts blood sugar
how honey imapcts blood sugar

Team Heald

Posted on

Jun 17, 2025

by

Medically Reviewed By:

Dr. Karamvir Goyal, Diabetologist

Table of content

Title
Title

Honey has long been cherished as a natural sweetener, a remedy in traditional medicine, and a symbol of sweetness in cultures worldwide. But when it comes to managing blood sugar levels, especially for people with diabetes, honey often sparks a question: Does honey raise blood glucose? Or could it actually help slow glucose absorption in the gut, acting as a natural shield to prevent sharp blood sugar spikes?

In this blog, we’ll explore the fascinating science behind honey’s effects on blood sugar, focusing on how certain compounds and enzymes in honey may slow down intestinal glucose absorption. Understanding these mechanisms can help you make informed choices about including honey in a blood sugar-friendly diet.

The Effect of Honey on Blood Sugar Levels: What You Need to Know

Honey is primarily made up of natural sugars, mainly fructose and glucose. Naturally, consuming sugar raises blood glucose levels, but honey is different from refined sugar in several important ways. It contains bioactive compounds, enzymes, antioxidants, and trace minerals that interact with how the body processes sugar.

Research shows that honey causes a slower, more gradual increase in blood glucose compared to pure glucose or table sugar. This difference in impact is linked to honey’s composition and how its compounds affect digestion and glucose absorption in the gut.

Does Honey Raise Blood Glucose Levels? Understanding the Science

Yes, honey does contain sugars that can raise blood glucose, but not all sugars act the same. Fructose, which makes up about 40% of honey, has a lower glycemic effect compared to glucose. Moreover, honey contains special enzymes that influence how sugar is digested and absorbed.

One of the key processes involved in blood sugar regulation is the digestion of carbohydrates by enzymes like alpha-glucosidase in the small intestine. These enzymes break down complex sugars into glucose, which is then absorbed into the bloodstream.

Certain compounds in honey have been found to inhibit the activity of alpha-glucosidase, effectively slowing carbohydrate breakdown. This leads to slower glucose absorption, preventing sudden blood sugar spikes after meals. This natural inhibition can make honey a potentially better option compared to other sweeteners that lack these beneficial enzymes.

A comprehensive review published in Oxidative Medicine and Cellular Longevity highlights that enzymes and polyphenols in honey can inhibit digestive enzymes such as alpha-glucosidase and alpha-amylase, thereby modulating glucose uptake in the gut and contributing to better blood sugar regulation.

Honey’s Glucose Index: A Natural Alternative to Sugar

The glycemic index (GI) measures how quickly a carbohydrate-containing food raises blood glucose levels. Foods with a high GI cause rapid spikes, while those with a low GI lead to a slower, steadier rise.

Honey’s GI varies depending on the floral source, but generally ranges between 35 to 58, which is lower than regular table sugar (GI ~65-70). This means honey raises blood sugar levels more slowly and steadily compared to refined sugar.

This lower GI is significant for people with diabetes or those monitoring blood sugar levels, as managing post-meal glucose spikes is crucial for overall health.

Here’s a quick comparison table of honey and other common sweeteners to put this in perspective:

Sweetener

Approximate Glycemic Index (GI)

Key Features

Glucose

100

Rapid blood sugar spike, pure glucose

Table Sugar (Sucrose)

65-70

Common refined sugar, moderate blood sugar rise

Honey

35-58

Contains fructose, enzymes; slower glucose rise

Agave Nectar

10-30

High fructose content, very low GI

Maple Syrup

54

Natural sweetener, moderate GI

The Role of Enzymes in Honey and Their Impact on Glucose Absorption

Honey is not just sugar; it’s a complex natural product packed with enzymes, antioxidants, and phytochemicals. One important enzyme is glucose oxidase, which plays a role in honey’s antimicrobial properties but also interacts with digestive processes.

Studies have highlighted that enzymes and polyphenols in honey can inhibit intestinal enzymes such as alpha-glucosidase and alpha-amylase. By slowing these enzymes, honey delays the digestion of carbohydrates into glucose.

This enzymatic activity acts like a “sweet shield,” modulating the speed at which glucose enters the bloodstream. This effect can help blunt postprandial (after-meal) blood sugar spikes, a key factor in diabetes management.

Honey and Diabetes: Can It Be Part of a Blood Sugar-Friendly Diet?

Given honey’s natural sugar content, it might seem counterintuitive to include it in a diabetes-friendly diet. However, research and clinical observations suggest that when consumed in moderation, honey’s unique properties may offer advantages over refined sugars.

A controlled clinical study by Al-Waili (2004) showed that replacing table sugar with honey in patients with type 2 diabetes led to improved blood glucose control and better lipid profiles. These benefits were attributed to honey’s antioxidant content and its ability to slow down glucose absorption through enzyme inhibition. 

Get our 5-point holistic program to naturally reverse type 2 diabetes — focusing on Diet, Activity, Sleep, Stress & Medication.

Reverse Diabetes

Still, it’s essential to:

  • Use honey sparingly and avoid excess

  • Choose raw, unprocessed honey to retain beneficial enzymes and compounds

  • Incorporate honey as part of a balanced diet rich in fiber, protein, and healthy fats that also help regulate blood sugar

Always consult your healthcare provider before making significant changes to your diet, especially if you have diabetes.

Conclusion: Harnessing Honey’s Potential for Better Blood Sugar Regulation

Honey is more than just a natural sweetener; it’s a complex food with the potential to positively influence blood sugar regulation. Thanks to its unique enzymes and bioactive compounds, honey can slow down glucose absorption in the gut, acting as a “sweet shield” that helps prevent sharp blood sugar spikes.

While honey does contain sugars that raise blood glucose, its lower glycemic index and enzyme-driven modulation make it a preferable alternative to refined sugars for many people.

Moderation is key, and incorporating honey thoughtfully into a balanced diet may provide both sweetness and metabolic benefits.

By understanding honey’s hidden powers, you can make smarter choices that satisfy your sweet tooth without compromising blood sugar control.

Footnote:
People with diabetes should use honey strictly in very calculated quantities and always monitor its effect on blood glucose, preferably using a Continuous Glucose Monitor (CGM) for safety and precision.

Popular Blogs

Comments

logo-Heald

Get Connected with us on:

Address:

Completum health Inc,
Tech Alpharetta
925 North Point Parkway,
Suite 130,
Alpharetta, GA 30005

© Copyright Heald. All Rights Reserved

logo-Heald

Get Connected with us on:

Address:

Completum health Inc,
Tech Alpharetta
925 North Point Parkway,
Suite 130,
Alpharetta, GA 30005

© Copyright Heald. All Rights Reserved

logo-Heald

Get Connected with us on:

Address:

Completum health Inc,
Tech Alpharetta
925 North Point Parkway, Suite 130, Alpharetta, GA 30005

© Copyright Heald. All Rights Reserved